Herbal formula named Zyflamend is patented and manufactured by New Chapter of Brattleboro , VT.
Zyflamend contains supercritical extracts of 10 herbs, which come from exceptionally pure sources (including the organic farm of New Chapter in Costa Rica).
Supercritical extraction is a whole-food approach to herbal supplementation.
Many companies, which are producing herbal supplements, isolate single elements from an herb and concentrate it.
Supercritical method used by New Chapter yields the fullest spectrum of beneficial phytonutrients in their natural profile. That kind of extraction, which doesn't use any chemical solvents, delivers a product which is super pure and super potent. Each capsule of Zyflamend contains extracts of ten herbs and all their most biologically active components.
They are concentrated in the ratio (on average) 250:1. One kilo of finished product originates from 250 kilos of plants.
By using only natural supercritical CO2 or traditional techniques of extraction, a final preparation is obtained in which all biologically active ingredients are present in the same proportions as in the wild. It doesn't include the so-called isolates which would unevenly affect the body by disturbing physiological balance .
Manufacturer of Zyflamend ( New Chapter ) assumes that nature offers the best remedies and various plants used in herbal medicine have proven to work safely over hundreds or even thousands of years. New Chapter tries to alter the plant output as little as possible to obtain the final product. The company's focus is on selecting the proper plants and the best extraction method.

The following 10 plants are used to produce Zyflamend:
Rosemary (Rosemarinus officinalis) - leaf
(rich in phenolic antioxidants)
Turmeric (Curcuma longa) - rhizome
(contains turmerons and curcuminoids),
Ginger (Zingiber officinale) - rhizome
(with zingiberen and many other pungent compounds),
Holy Basil (Ocimum sanctum) - leaf
(contains ursolic acid),
Green tea (Camellia sinensis) - leaf
(with many powerful polyphenols),
Hu Zhang (Polygonum cuspidatum) - root & rhizome
(probably the richest plantal source of resveratrol),
Chinese Goldthread (Coptis chinensis) - root
(contains berberine),
Barberry (berberis vulgaris) - root
(a rich source of berberine),
Oregano (Origanum heracleoticum) - leaf
(source of many natural compounds regulating proper inflammatory response and antioxidants),
Baikal Skullcap (Scutellaria baicalensis) - root
(contains baicalein complex including baicalein and baicalin and wogonin).

Zyflamend has been tested extensively in clinical trials.
It has been proven that Zyflamend helps regulate inflammatory process, and is beneficial for the health of bones, joints , heart, the whole cardiovascular system, immune system, prostate, breast, liver, digestion, lungs, brain and skin.
Chronic inflammation is associated with aging and promotes uncontrolled cell division which can in turn result in cancer.
Plants included in this best selling in the United States herbal supplement are derived from various healing systems.
The way these plants are combined reinforces their benefits so that their combination is greater than the sum of individual herbs. They work synergistically. It was found, for example, that turmeric and green tea enhance each other's benefits eight times.
So far at least 78 biologically active substances extracted from Zyflamed have been found to have strong antioxidant activity, promote glucose metabolism, help detoxification and even promote good mood. Action which controls a healthy inflammatory response is multidimensional. This means that the wealth of different substances present in the formulation inhibits multiple pathways of an inflammatory response in a variety of locations.

Zyflamend is used primarily to reduce chronic joint inflammation which causes degenerative joint disease, rheumatoid arthritis or any other inflammatory joint disease (for example: psoriatic arthritis).
Bones and joints undergo continuous remodeling throughout life. Our skeletal system is simultaneously built and destroyed. It has been proven that the skeletal system replaces itself approximately every seven to ten years. People over 30 lose on average 0.5-1% of their bone mass annually.
Chronic inflammation greatly affects bone metabolism by activation of RANKL substance. RANKL molecule stimulates osteoclasts which are cells responsible for bone resorption.
In vitro study conducted by University of Texas MD Anderson Cancer Center shows that Zyflamend inhibits RANKL production and may thus reduce excessive production of bone-destroying osteoclasts.
Zyflamend may thereby inhibit joint and bone damage present in degenerative disease of joints and bones and in their other chronic inflammatory disorders.

It is essential for joint health to provide substances necessary for proper cartilage regeneration, such as glucosamine sulfate, chondroitin sulfate, hyaluronic acid and MSM.
Supplements containing above chemical compounds can be more effective if taken with Zyflamend which also works better if accompanied by supplements featuring substances needed for bone mineralization.
Excellent supplement with above-mentioned capabilities is (also New Chapter's) Bone Strength Take Care®.
The level of calcium in the blood is important not only for bone health but also for proper functioning of nerves, muscles, hormones, blood clotting, a healthy heart and circulatory system.
Therefore, the body's physiological processes tend to maintain the same, correct level of calcium in blood.
If dietary intake is insufficient, then calcium is extracted from bones, which in the long run can lead to decreased bone density (mineralization).
Bone Strength Take Care® contains plant-sourced calcium which is much better aborbed by the body than limestone-derived calcium, because plant-sourced, porous calcium is part of a matrix of minerals organized in a honeycomb structure. Most other calcium supplements which are derived from limestone have a flat architecture.
The porous honeycomb structure provides a large contact surface with the gastric acid, which facilitates calcium dissolution (necessary for its proper absorption from the gastrointestinal tract).
Bone Strength Take Care® contains also magnesium, trace elements, vitamin K1 and K2 (because of which calcium is deposited in bones instead of blood vessels) and vitamin D3 (required for proper absorption of calcium and bone metabolism).

It is currently known that chronic inflammation in human body is linked to the development of several cancers. These include cancer of the prostate, breast, lung, liver, stomach, pancreas, esophagus and colon.
Doctors in Germany use the herb Boswellia serrata (anti-inflammatory - like Zyflamend) to reduce the size of a brain tumor in order to make further treatment easier.
Most of the signs and symptoms of glioblastoma multiforme and astrocytoma result from swelling which is to a very large extent related to the strong inflammation of the tumor and its surroundings in brain.

Zyflamend has probably also direct antineoplastic effect which has been confirmed by numerous scientific studies at renowned medical centers.

Adequate inflammatory response is not a disease and is necessary for the human body to function properly.
The problem occurs when there is too much inflammation mainly related to a diet rich in fat, meat and dairy products.
Excessive inflammatory response is mainly caused by abnormal metabolism of arachidonic acid, which is processed in the body by enzymes (called cyclooxygenases and lipoxygenases) into prostaglandins and leukotrienes.
These substances regulate the contractility of blood vessels and are involved in inflammatory and allergic reactions.
Zyflamend is considered an ideal supplement inhibiting their excessive production and thus regulating healthy inflammatory reaction of each organ and body system.
In the long run it is mainly chronic and silent inflammatory processes which are very detrimental to our health.

During many years of using Zyflamend by tens of thousands of people no serious side effects were observed and Zyflamend is considered to be a safe dietary supplement. This opinion comes from medical centers, which checked Zyflamend's performance in clinical trials, and from people taking this preparation and expressing their opinion about it on the Internet.

Zyflamend inhibits both cyclooxygenases (COX) and lipoxygenases (LOX). It also probably influences all aspects of excessive inflammatory reaction of the body.
Synthetic anti-inflammatory drugs, available with or without a prescription, affect body differently.
These include Aspirin, Ibuprofen, Vioxx (fortunately available only by prescription), Naproxen and similar pharmaceuticals, known as nonsteroidal anti-inflammatory drugs (NSAIDs).
These synthetic drugs are mainly used as analgesics (for pain), antipyretics (for fever) and anti-inflammatories.
Their usage is related to an increased risk of gastrointestinal bleeding, cerebral hemorrhage, blood clots, myocardial infarction, sudden death (observed while using Vioxx and other blockers of COX-2 and also during a long term use of Ibuprofen in larger doses).
Why do synthetic drugs have such dangerous side effects?
This is particularly evident in the way completely natural (non-synthetic) Zyflamend affects the body.
Zyflamend influences inflammation gently, on its numerous levels and in many locations of biochemical and physiological processes.
Zyflamend may help get rid of that part of inflammation which is excessive and harmful. It does not work as strongly as non-steroidal anti-inflammatory drugs and does not work fast. This complex herbal formulation is not a powerful pain inhibitor. Its use, however, helps create a situation in the body in which prescription drugs may be not needed or may work in much smaller, less harmful doses.
All synthetic non-steroidal anti-inflammatory drugs are single chemical substances and can be described with a chemical formula (which is required by FDA to register a drug as a medicine treating and preventing diseases).
As single chemical substances, synthetic drugs can only block single paths of inflammatory response (for example one of cycloogenases but not LOX or other COX enzymes). They usually give fast and expected results because their action is much stronger at a given site than would be in case of Zyflamend.
However, the body does not get fooled so easily. Biochemical and physiological processes blocked at one place, seem to run in many alternative ways in an uncontrolled manner. Single synthetic chemical substance may knock the body out of balance necessary for true health.

The use of Zyflamend is not devoid of side effects.
They are, however, rare and much less dangerous than those which may be associated with taking synthetic non-steroidal anti-inflammatory drugs.
To date, there was not a single life-threatening case described associated with taking Zyflamend, even when this formulation was taken for many months.
In case of any side effects, the most commonly reported symptoms were gastrointestinal. They may be the following: bubbling feeling in the intestines, flatulence, bad taste in the mouth, heartburn, and diarrhea. It was noticed that these symptoms occurred less often when Zyflamend was taken with a glass of water, during a meal.
Allergic reaction to Zyflamend ingredients may occur. It is therefore recommended to start with smaller doses. For example: one capsule daily for a week and afterwards one capsule in the morning at breakfast and one in the evening at dinner or supper.

Zyflamend is currently the best selling herbal supplement in the United States. It comprises of supercritical exctracts of 10 herbs originating in various healing systems.

Zyflamend and related suplements (listed below) is used to control proper inflammatory response in the whole body.

Substances released during longterm, silent and excessive inflammation cause premature aging and lead to the development of numerous degenerative diseases and cancers.

Zyflamend's numerous ingredients gently reduce the body's excessive inflammatory response. These ingredients work synergistically and in many locations of biochemical and physiological processes which are pathways of inflammation.

Synthetic anti-inflammatory pharmaceuticals (steroid and non-steroid) are single chemical compounds which inhibit inflammatory response in specific locations of biochemical processes of the body. This action can disturb the body's homeostasis (its balance). Pharmaceuticals have many dangerous side effects, especially if a person uses them in high doses and over long periods of time.